SPP 2395 – Team

Actin cytoskeleton disturbance as a driver of cellular dysfunction and cell state diversity in microglia

Caroline Bergner, Stefan Nessler, Christine Stadelmann-Nessler

Dr. Caroline Bergner

Aberrant microglia function as drivers of neuroaxonal degeneration in diseases of the white matter

Microglia instruct the toxic microenvironment in transplantable leukodystrophies

Caroline Bergner, Stefan Nessler, Christine Stadelmann-Nessler

Dr. Dr. Lukas Bunse

Microglial immunosurveillance of oncogenic isocitrate dehydrogenase (CONVINCE-IDH)

Lukas Bunse, Michael Platten

Trained Spp1+ microglial immunity in glioma – (TRAINSPOTTING)

Michael Platten, Lukas Bunse

Dr. Felix Nebeling

Spatio-temporal profiling of microglial heterogeneity and dynamics in glioblastoma

Felix Nebeling, Martin Fuhrmann

Dr. Felix Strübing

Spatiotemporally resolved microglial diversity and reciprocal interaction with the noradrenergic system in Alzheimer’s disease

Lars Paeger, Felix Strübing

Dr. Ilon Liu

Genetic and non-genetic determinants of brain cancer-associated clonal myeloid cell dynamics and plasticity

Ilon Liu, Leif S. Ludwig

Dr. Lars Päger

Spatiotemporally resolved microglial diversity and reciprocal interaction with the noradrenergic system in Alzheimer’s disease

Lars Paeger, Felix Strübing

Dr. Leif S. Ludwig

Genetic and non-genetic determinants of brain cancer-associated clonal myeloid cell dynamics and plasticity

Ilon Liu, Leif S. Ludwig

Epigenomic states of microglia driving central nervous system repair in humans

Leif S. Ludwig

Dr. Sabina Tahirovic

T cells as modulators of microglia-mediated neurodegeneration in Niemann Pick type C (NPC) disease

T cells as modulators of microglial reactivity in Alzheimer’s disease

Dr. Sophie Crux-Daseking

The role of microglial cytoskeleton proteins ADF/Cfl1 in learning and memory

The role of microtubule cytoskeleton modulation in microglia and its effect on cognition

Caroline Bergner, Stefan Nessler, Christine Stadelmann-Nessler

Dr. Stefan Nessler

Aberrant microglia function as drivers of neuroaxonal degeneration in diseases of the white matter

Microglia instruct the toxic microenvironment in transplantable leukodystrophies

Caroline Bergner, Stefan Nessler, Christine Stadelmann-Nessler

PD Dr. Corinne Benakis

Chronic exposure to environmental pollutants and microglial molecular reprogramming in ischemic stroke

Corinne Benakis

Prof. Dr. Alexander Mildner

Influence of cytokines on microglial metabolism during Alzheimer’s disease

Alexander Mildner

Microglial lipid metabolism during physiological and pathological conditions

Alexander Mildner

Prof. Dr. Antje Grosche

Microglial dynamics in retinal diseases: Müller cells and T cells as local and peripheral interacting partners

Cornelia Deeg, Antje Grosche

Prof. Dr. Ari Waisman

The role of CYLD and A20 in microglia in aging and autoimmunity

Ari Waisman

The deubiquitinating enzyme A20 as gate keepers of central nervous system homeostasis

Ari Waisman

Prof. Dr. Arthur Liesz

T cells as modulators of microglial reactivity in Alzheimer’s disease

T cells as modulators of microglia-mediated neurodegeneration in Niemann Pick type C (NPC) disease

Caroline Bergner, Stefan Nessler, Christine Stadelmann-Nessler

Prof. Dr. Christine Stadelmann-Nessler

Aberrant microglia function as drivers of neuroaxonal degeneration in diseases of the white matter

Microglia instruct the toxic microenvironment in transplantable leukodystrophies

Caroline Bergner, Stefan Nessler, Christine Stadelmann-Nessler

Prof. Dr. Cornelia Deeg

Microglial dynamics in retinal diseases: Müller cells and T cells as local and peripheral interacting partners

Cornelia Deeg, Antje Grosche

Prof. Dr. Doron Merkler

CD8+ tissue-resident T-cell regulation of microglia function

Mikael Simons, Doron Merkler

Prof. Dr. Frank Bradke

The cytoskeleton as a signaling node that contributes to microglia activation and diversity

Actin cytoskeleton disturbance as a driver of cellular dysfunction and cell state diversity in microglia

Prof. Dr. Josef Priller

A novel in vivo human-mouse chimeric brain model to study human microglia specification and contributions to neuropsychiatric disease

Elucidating sex-specific and disease-associated human microglia phenotypes and their contribution to Rett Syndrome

Michael Kiebler, Jovica Ninkovic

Prof. Dr. Jovica Ninkovic

The role of translation in shaping microglial activation states during neuroinflammation

Prof. Dr. Marco Prinz

Charting CNS-endogenous innate immune responses across cells and species

Marco Prinz

Prof. Dr. Martin Fuhrmann

The role of microglial cytoskeleton proteins ADF/Cfl1 in learning and memory

The role of microtubule cytoskeleton modulation in microglia and its effect on cognition

Felix Nebeling, Martin Fuhrmann

Spatio-temporal profiling of microglial heterogeneity and dynamics in glioblastoma

Prof. Dr. Michael Kiebler

The role of translation in shaping microglial activation states during neuroinflammation

Michael Kiebler, Jovica Ninkovic

Prof. Dr. Michael Platten

Microglial immunosurveillance of oncogenic isocitrate dehydrogenase (CONVINCE-IDH)

Lukas Bunse, Michael Platten

Trained Spp1+ microglial immunity in glioma – (TRAINSPOTTING)

Michael Platten, Lukas Bunse

Prof. Dr. Mikael Simons

CD8+ tissue-resident T-cell regulation of microglia function

Mikael Simons, Doron Merkler

Prof. Dr. Simon Schäfer

A novel in vivo human-mouse chimeric brain model to study human microglia specification and contributions to neuropsychiatric disease

Elucidating sex-specific and disease-associated human microglia phenotypes and their contribution to Rett Syndrome