Publications

Dinkel, L., Hummel, S., Zenatti, V., Malara, M., Tillmann, Y., Colombo, A., Monasor, L. S., Suh, J. H., Logan, T., Roth, S., Paeger, L., Hoffelner, P., Bludau, O., Schmidt, A., Muller, S. A., Schifferer, M., Nuscher, B., Njavro, J. R., Prestel, M., Bartos, L. M., Wind-Mark, K., Slemann, L., Hoermann, L., Kunte, S. T., Gnorich, J., Lindner, S., Simons, M., Herms, J., Paquet, D., Lichtenthaler, S. F., Bartenstein, P., Franzmeier, N., Liesz, A., Grosche, A., Bremova-Ertl, T., Catarino, C., Beblo, S., Bergner, C., Schneider, S. A., Strupp, M., Di Paolo, G., Brendel, M., & Tahirovic, S. (2024):
Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
Sci Transl Med, 16(776): eadl4616
DOI:10.1126/scitranslmed.adl4616

Lerma-Martin, C., Badia, I. M. P., Ramirez Flores, R. O., Sekol, P., Schäfer, P. S. L., Riedl, C. J., Hofmann, A., Thäwel, T., Wünnemann, F., Ibarra-Arellano, M. A., Trobisch, T., Eisele, P., Schapiro, D., Haeussler, M., Hametner, S., Saez-Rodriguez, J. & Schirmer, L. (2024):
Cell type mapping of inflammatory muscle diseases highlights selective myofiber vulnerability in inclusion body myositis.
Nat Neurosci: online first
DOI:10.1038/s41593-024-01796-z

Cuevas-Rios, G., Assale, T. A., Wissfeld, J., Bungartz, A., Hofmann, J., Langmann, T., & Neumann, H. (2024):
Decreased sialylation elicits complement-related microglia response and bipolar cell loss in the mouse retina.
Glia 72(12):2295-2312
DOI: 10.1002/glia.24613

Kedia, S., Ji, H., Feng, R., Androvic, P., Spieth, L., Liu, L., Franz, J., Zdiarstek, H., Anderson, K. P., Kaboglu, C., Liu, Q., Mattugini, N., Cherif, F., Prtvar, D., Cantuti-Castelvetri, L., Liesz, A., Schifferer, M., Stadelmann, C., Tahirovic, S., Gokce, O. and Simons, M. (2024):
T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis.
Nat Neurosci 27, 1468–1474
DOI: 10.1038/s41593-024-01682-8

Masala, N., Mittag, M., Giovannetti, E. A., O'Neil, D. A., Distler, F. J., Rupprecht, P., Helmchen, F., Yuste, R., Fuhrmann, M., Beck, H., Wenzel, M., & Kelly, T. (2024):
Aberrant hippocampal Ca(2+) microwaves following synapsin-dependent adeno-associated viral expression of Ca(2+) indicators.
Elife 13
DOI: 10.7554/eLife.93804

Wischnewski, S., Thäwel, T., Ikenaga, C., Kocharyan, A., Lerma-Martin, C., Zulji, A., Rausch, H. W., Brenner, D., Thomas, L., Kutza, M., Wick, B., Trobisch, T., Preusse, C., Haeussler, M., Leipe, J., Ludolph, A., Rosenbohm, A., Hoke, A., Platten, M., Weishaupt, J. H., Sommer, C. J., Stenzel, W., Lloyd, T. E., & Schirmer, L. (2024):
Cell type mapping of inflammatory muscle diseases highlights selective myofiber vulnerability in inclusion body myositis.
Nat Aging, 4(7), 969-983
DOI: 10.1038/s43587-024-00645-9

Mariano, V., Kanellopoulos, A. K., Ricci, C., Di Marino, D., Borrie, S. C., Dupraz, S., Bradke, F., Achsel, T., Legius, E., Odent, S., Billuart, P., Bienvenu, T., & Bagni, C. (2024):
Intellectual Disability and Behavioral Deficits Linked to CYFIP1 Missense Variants Disrupting Actin Polymerization.
Biol Psychiatry, 95(2), 161-174
DOI: 10.1016/j.biopsych.2023.08.027

Sankowski, R., Süß, P., Benkendorff, A., Böttcher, C., Fernandez-Zapata, C., Chhatbar, C., Cahueau, J., Monaco, G., Gasull, A. D., Khavaran, A., Grauvogel, J., Scheiwe, C., Shah, M. J., Heiland, D. H., Schnell, O., Markfeld-Erol, F., Kunze, M., Zeiser, R., Priller, J., & Prinz, M. (2024):
Multiomic spatial landscape of innate immune cells at human central nervous system borders.
Nat Med 30(1)
DOI: 10.1038/s41591-023-02673-1

Lawrence, A. R., Canzi, A., Bridlance, C., Olivié, N., Lansonneur, C., Catale, C., Pizzamiglio, L., Kloeckner, B., Silvin, A., Munro, D. A. D., Fortoul, A., Boido, D., Zehani, F., Cartonnet, H., Viguier, S., Oller, G., Squarzoni, P., Candat, A., Helft, J., Allet, C., Watrin, F., Manent, J. B., Paoletti, P., Thieffry, D., Cantini, L., Pridans, C., Priller, J., Gélot, A., Giacobini, P., Ciobanu, L., Ginhoux, F., Thion, M. S., Lokmane, L., & Garel, S. (2024):
Microglia maintain structural integrity during fetal brain morphogenesis.
Cell 187(4), 962-980.e919
DOI: 10.1016/j.cell.2024.01.012

Ohm, M., Hosseini, S., Lonnemann, N., He, W., More, T., Goldmann, O., Medina, E., Hiller, K., & Korte, M. (2024):
The potential therapeutic role of itaconate and mesaconate on the detrimental effects of LPS-induced neuroinflammation in the brain.
J Neuroinflammation 21(1), 207
DOI: 10.1186/s12974-024-03188-3

Cheng, J., Li, M., Motta, E., Barci, D., Song, W., Zhou, D., Li, G., Zhu, S., Yang, A., Vaillant, B. D., Imhof, A., Forné, I., Spiegl-Kreinecker, S., Zhang, N., Katayama, H., Bhat, K. P. L., Flüh, C., Kälin, R. E., & Glass, R. (2024):
Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling.
Cell Rep Med 5(8): 101658
DOI: 10.1016/j.xcrm.2024.101658

Bitar, L., Puig, B., Oertner, T. G., Dénes, Á., & Magnus, T. (2024):
REVIEW: Changes in Neuroimmunological Synapses During Cerebral Ischemia.
Transl Stroke Res :
DOI: 10.1007/s12975-024-01286-1

Ludwig, N., Cucinelli, S., Hametner, S., Muckenthaler, M. U., & Schirmer, L. (2024):
REVIEW: Iron scavenging and myeloid cell polarization.
Trends Immunol 45(8), 625-638
DOI: 10.1016/j.it.2024.06.006

Wißfeld, J., Abou Assale, T., Cuevas-Rios, G., Liao, H., & Neumann, H. (2024):
REVIEW: Therapeutic potential to target sialylation and SIGLECs in neurodegenerative and psychiatric diseases.
Front Neurol 15 1330874
DOI: 10.3389/fneur.2024.1330874

Mingo, Y. B., Gabele, L., Lonnemann, N., Brône, B., Korte, M., & Hosseini, S. (2024):
The effects of urolithin A on poly I:C-induced microglial activation.
Front Cell Neurosci 18, 1343562
DOI: 10.3389/fncel.2024.1343562

Gabele, L., Bochow, I., Rieke, N., Sieben, C., Michaelsen-Preusse, K., Hosseini, S., & Korte, M. (2024):
H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro.
Front Cell Neurosci 18, 1444876
DOI: 10.3389/fncel.2024.1444876

Hofmann, A., N. Krajnc, A. Dal-Bianco, C. J. Riedl, T. Zrzavy, C. Lerma-Martin, G. Kasprian, C. E. Weber, F. Pezzini, F. Leutmezer, P. Rommer, G. Bsteh, M. Platten, A. Gass, T. Berger, P. Eisele, R. Magliozzi, L. Schirmer and S. Hametner (2023):
Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis.
Acta Neuropathol 146(5):707-724
DOI: 10.3389/fphar.2023.1142639

Zhao, B., Kilian, M., Bunse, T., Platten, M., & Bunse, L. (2023):
REVIEW: Tumor-reactive T helper cells in the context of vaccination against glioma.
Cancer Cell 41(11), 1829-1834
DOI: 10.1016/j.ccell.2023.09.013

Priller, J., Schäfer, S., & Safaiyan, S. (2023):
REVIEW: ature and immune mechanisms of mental illnesses.
Nervenarzt 94(11), 1010-1018
DOI: 10.1007/s00115-023-01554-9

Schafer, S. T., A. A. Mansour, J. C. M. Schlachetzki, M. Pena, S. Ghassemzadeh, L. Mitchell, A. Mar, D. Quang, S. Stumpf, I. S. Ortiz, A. J. Lana, C. Baek, R. Zaghal, C. K. Glass, A. Nimmerjahn and F. H. Gage (2023):
An in vivo neuroimmune organoid model to study human microglia phenotypes.
Cell 186(10): 2111-2126.e2120.
DOI: 10.1016/j.cell.2023.04.022

Hosseini, S. and M. Korte (2023):
REVIEW: How viral infections cause neuronal dysfunction: a focus on the role of microglia and astrocytes.
Biochem Soc Trans 51(1): 259-274.
DOI: 10.1042/bst20220771

Kilian, M., R. Sheinin, C. L. Tan, M. Friedrich, C. Krämer, A. Kaminitz, K. Sanghvi, K. Lindner, Y. C. Chih, F. Cichon, B. Richter, S. Jung, K. Jähne, M. Ratliff, R. M. Prins, N. Etminan, A. von Deimling, W. Wick, A. Madi, L. Bunse and M. Platten (2023):
MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors.
Cancer Cell 41(2): 235-251.e9.
DOI: 10.1016/j.ccell.2022.12.007

Nebeling, F. C., Poll, S., Justus, L. C., Steffen, J., Keppler, K., Mittag, M., & Fuhrmann, M. (2023):
Microglial motility is modulated by neuronal activity and correlates with dendritic spine plasticity in the hippocampus of awake mice.
Elife 12
DOI: 10.7554/eLife.83176

Wang, M., Gage, F. H., & Schafer, S. T. (2023):
REVIEW: Transplantation Strategies to Enhance Maturity and Cellular Complexity in Brain Organoids.
Biol Psychiatry 93(7), 616-621
DOI: 10.1016/j.biopsych.2023.01.004

Griffin, J. M., Hingorani Jai Prakash, S., Bockemühl, T., Benner, J. M., Schaffran, B., Moreno-Manzano, V., Büschges, A., & Bradke, F. (2023):
Rehabilitation enhances epothilone-induced locomotor recovery after spinal cord injury.
Brain Commun 5(1), fcad005
DOI: 10.1093/braincomms/fcad005

Demuth, L., M. Ohm, K. Michaelsen-Preusse, K. Schulze, P. Riese, C. A. Guzmán, M. Korte and S. Hosseini (2023):
Influenza vaccine is able to prevent neuroinflammation triggered by H7N7 IAV infection.
Front Pharmacol 14: 1142639.
DOI: 10.3389/fphar.2023.1142639

Fuhrmann, M., Gockel, N., Arizono, M., Dembitskaya, Y., Nägerl, U. V., Pennacchietti, F., Damenti, M., Testa, I., & Willig, K. I. (2022):
REVIEW: Super-Resolution Microscopy Opens New Doors to Life at the Nanoscale.
J Neurosci 42(45), 8488-8497
DOI: 10.1523/jneurosci.1125-22.2022

Göttert, R., Fidzinski, P., Kraus, L., Schneider, U. C., Holtkamp, M., Endres, M., Gertz, K., & Kronenberg, G. (2022):
Lithium inhibits tryptophan catabolism via the inflammation-induced kynurenine pathway in human microglia.
Glia 70(3), 558-571.
DOI: 10.1002/glia.24123

Vieira, J. R., Shah, B., Dupraz, S., Paredes, I., Himmels, P., Schermann, G., Adler, H., Motta, A., Gärtner, L., Navarro-Aragall, A., Ioannou, E., Dyukova, E., Bonnavion, R., Fischer, A., Bonanomi, D., Bradke, F., Ruhrberg, C., & Ruiz de Almodóvar, C. (2022):
Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development.
Neuron 110(24), 4074-4089.e4076
DOI: 10.1016/j.neuron.2022.12.005